Side Effects of Marijuana Assignment Example | Topics and Well Written Essays - 750 words

Side Effects of Marijuana - Assignment Example An overdose of the drug may lead to hallucination and the loss of self identity, overdose occurs when the drug is eaten because the user can take in a larger dose at once, The use of the drug is also addictive which is evident whereby the individual experiences an uncontrollable crave for the drug, marijuana addiction cycle is very powerful whereby the individuals find it impossible to stop the habit. The chemical compound of the drug also disrupts the proper function of the brain. The use of the drug causes chemical imbalances in the brain, as a result, the individual experiences difficulties in learning, difficulties in remembering, and the lack to quickly respond. The drug use also causes pain and individuals are required to take up more other drugs to stop the pain as a result the drug may lead to depression. When the drug is smoked it is absorbed into the bloodstream and enters the brain, the chemical compound delta 9 tetrahydrocannabinol interact with brain receptors... art rate and the breathing rate, as a result, the individual is more prone to heart attacks and other heart problem, this effect is caused by the chemicals in the drug which causes an increase in body processes, as a result, the drug taxes the body more and therefore speeding up the aging process.

The Horns of a Rhino Essay Example for Free

The Horns of a Rhino Essay What large mammal has tough, thick, light-grey skin, and has two large horns coming out of its nose? After reading that description, ideally one’s answer should be a rhinoceros. In most cases, we always picture a rhinoceros to have two horns and light-grey skin, but often forget about the rhinoceros who have darker colored skin and only one horn. There were once hundreds of rhinoceros species however, only five species exist today. The African Black and White rhinos, and the Sumatran rhinos have two horns, but the Indian and Javan rhinos from Asia only have one. Why is it that some rhinoceros have two horns while others only have one? I believe that the second horn certain rhinoceros have first came along as a beneficial mutation, and then eventually due to natural selection and allopatric speciation, certain rhinoceros now have two horns instead of one. The rhinos that existed about 60 million years ago looked more like today’s horses than the typical rhinoceros we are familiar with. This would explain their unusual diet and rather fast speeds. The weight of a rhino ranges from 750 pounds to 8000 pounds. The expectation should be that for such a massive animal, they would be rather slow; however, that is not the case at all. Similar to a horse, Rhinos can be rather fast as well. When charging at an animal, the Rhino could reach speeds of 56 km/h. With such violent and defensive ways, it is assumed that rhinos are meat eaters; however, that is not the case either. Similar to horses, rhinos are herbivores. They like to eat grass, foliage of trees, and bushes. Eating habits and speed are behavioral characteristics from their ancestors that have remained the same. There are even some physical characteristics that have remained the same like being an odd-toed ungulate. While so many characteristics were carried over from the rhinoceros’ ancestors, there are also many new changes that have evolved; the most significant one is the extra horn. I believe that the extra horn came along as a beneficial mutation. When two ancestors of the rhinoceros with a single horn mated, there could have been a mistake in the replication of their DNA and resulted in the extra horn growing above the offspring’s nose. According to Lamarck’s second principle: The Inheritance of Acquired Characteristics, individuals could pass on to their offspring characteristics they had acquired during their lives. His theory may be incorrect but it helps explain that a species evolves in response to its environment, and becomes better adapted to that environment. The rhinoceros may have started with only one horn on its nose but because of the environment it lived in and the strong need for an extra horn for protection, over time the horn it once had evolved into two horns that we see now. Since rhinoceros are herbivores, they would never need to hunt for prey. Lions who are carnivores hunt regularly for their food, have many experiences fighting and know how to defend themselves. In a situation where a lion and a rhino battles, the rhino would have no way of defending itself for it has less experience fighting, less power than the lion, and less flexibility. This is why there is such a strong need for an extra horn. The horn would act as protection and by being able to charge at an animal with both horns, there would be an increase in the rhino’s chance of survival. According to Charles Darwin’s theory of evolution by natural selection, nature favors the reproductive success of some individuals within a population over others. In this case, nature would select against those with only one horn in this geographic area for those are the rhinoceros who are less strong defensively, and will not be able to survive in that particular area. So eventually, sexual selection will factor into the evolution of the rhino and females would only want to mate with rhinoceros who have two horns, resulting in offspring that will have a better chance of surviving and battling against more powerful animals in their habitat. It is known that the Earth didn’t always look this way. The Earth was once a super continent and overtime, it has broken up into separate pieces of land which are the continents and islands that we know now. It is very likely that the separation of land also separated the population of rhinoceros. This allopatric speciation separated the rhinoceros into two geographically isolated populations. Those who were separated to where we now call â€Å"Africa† had the beneficial mutation of an extra horn. This mutation however, was only shared among themselves because once populations are physically separated, they can no longer exchange genetic information. Rhinoceros who went off to Asia did not develop this mutation, and even if they did, it wouldn’t have been very beneficial to them in any way. While African rhinos tend to feed low to the ground, Asian rhinos usually feed off leaves higher above the ground. If the Asian rhinos did have this mutation, it could act as a barrier from getting food. Allopatric speciation not only affected the rhinoceros’ physical characteristics but behavioral characteristics as well. Studies show that in general, African rhinos are more aggressive than Asian rhinos. Therefore the different geographic areas these rhinos live in affect both physical and behavioral characteristics of each species. In conclusion, the reason some rhinoceros have two horns while others have one is because of their geographic location. While rhinos in Africa developed this mutation, rhinos in Asia did not. Allopatric speciation also did not allow the exchange of this new gene between the population of the two geographic areas. Hence, why most Asian rhinos have one horn and African rhinos have two. African rhinos require the extra horn while rhinos in Asia can make do with just their bottom teeth for defensive purposes. Rhinos in Asia won’t ever come across the same animals the Rhinos in Africa do, so the different species don’t share the same need of the horn. Could it be that one day all species of rhinoceros will require that extra horn?

History of Anabolic Steroids Misuse and Drug Testing

History of Anabolic Steroids Misuse and Drug Testing Introduction: History of drug abuse Drug abuse in sport is not a recent issue. In Ancient Greece, the Olympic athletes used special diets (herbs,mushrooms and sesame seeds) to improve their physical performance. The gladiators in the Roman times, consumed stimulants to reduce fatigue.(1,2) South American Indians used coca leaves to enhance stamina.(2) During the nineteenth century, drug abuse became a great problem. Caffeine, strychnine, alcohol, cocaine, opium, and oxygen were used by swimmers, runners and cyclists to increase performance.(1,2) In 1896, the cyclist Arthur Linton was the first reported fatality case in sport from strychnine intake which was administered by his coach.(1) Later on, in 1904, the runner Thomas Hicks, was near to death in Olympic Marathon in St Louis USA, from use of strychnine and brandy.(1) During the Second World War, amphetamine consumption started by the troops to reduce their fatigue. In 1940s and 1950s, amphetamines substitute other drugs in its use in sport.( became the choice over other drugs). (1) Reported deaths from amphetamine abuse was in 1964, the Danish cyclist knut Jensen at Rome Olympics died on the opening day of the games. In 1967, the British cyclist Tommy Simpson, at Tour de France, died from amphetamine abuse. After Simpson’s death, the International Olympic Committee took an action and the first list of banned substances was published in 1968.(1,3) In 1950s, a new class was misused by athletes and weightlifters to increase muscle size and strength and this class named anabolic steroids;(1) in 1964, there was suspect for use of anabolic steroid in Summer Olympics in Tokyo due to the increase in muscle mass of the athletes.(3) Top scandals in drug abuse 1. East German athletes(4,5,6) From 1972 to 1988, the East German which was a country of 17 million populations, won 20 to 40 gold medals in 4 years and became a country competing the United States and Soviet Union. Manfred Ewald who was the head of Olympic sport committee in East Germany, and Dr. Manfred Hoeppner who was the sports doctor at that time, were responsible about giving the athletes banned substances intentionally without their knowledge. This results in severe complications in the athlete’s health such as liver dysfunction, cancer, hormonal changes and infertility. From 1966 and on, many doctors and coaches in East German follow a plan which was sponsored by the government known as â€Å"systematic and overall doping in competitive sports†. After the collapse of East German and Berlin Wall fall in 1989, many athletes confessed about the pills and injections that were given to them. Kornelia Ender, Barbara Krause and Carola Nitschke were three of the thousands of East German athletes who had provided with steroids. Heidi Kreiger was also one of the athletes that was provided with steroids heavily and this was the main reason that force her to make sex-alteration operation. 2. Pan American Games in 1983 IOC included testosterone in the banned list in 1983 and it was the first endogenous substance to be tested at that time. The test was based on measuring the testosterone to epitestosterone (T/E) ratio. (1) The first drug testing for steroids was at the Pan America Games in Caracas and Venezuela in 1983. Around 15 athletes were caught at these games. Jeff Michaels, the American weightlifter, and Guy Greavette, the Canadian weightlifter, were tested positive for steroids. They returned their medals and being suspended for 2 years. (5,7) Many athletes of the U.S track-and-field team withdrew from the game rather than being captured. (7) 3. Ben Johnson’s scandal In 1988, the Canadian Ben Johnson was stripped of his gold medal at 100 meters after he has been tested positive for the anabolic steroid stanozolol at Seoul Olympics. Johnson has been banned from competition for 2 years.(7) 4. Michelle Smith: the Irish swimmer(5,7) In 1998, the Olympic champion swimmer Michelle Smith was tested positive for banned substance at her home through out-of-competition testing. The test was positive for alcohol in an amount that would be fatal if taken by an athlete. So FINA, the international governing body for swimming, concluded that the urine sample was treated with alcohol as a masking agent and Smith has been suspended for four years. 5. Chinese swim team(5,7) The Chinese national swim team has been used anabolic steroids, erythropoietin and human growth hormone in the last 15 years. In 1992 Barcelona Olympics and 1994 world championships, china won a high number of gold medals. In world swimming championships, a world records was set by women swimmers, and this causes suspect that they were using drugs. In 1994 at Asian Games, eleven athletes were caught as drug abusers for dihydrotestosterone. Since 1990,over 40 Chinese swimmers were tested positive for abused drugs and at that time china reached the peak for drug abuse over the swimming countries. 6. Tour de France(5) Doping by cyclists arises since 1967 after Simpson death at Tour de France due to amphetamine misuse. Drug abuse by cyclists continues and in summer 1998, the Festina cycling team was pushed out from the competition at Tour de France after the French Officials found EPO in their masseur’s car. After investigations, six of Festina’s nine riders confessed that they had taken abused drugs. Later on, the leader also has failed drug tests for anabolic steroids. Also in 2002, Stefano Garzelli, the leader of the Vini Caldirola team, has failed drug test for probenecid, a diuretic which is used as a masking agent. Also in the same year at Tour de France, the Spanish cyclist Igor Gonzalez de Galdeano, was tested positive for anti-asthmatic drug. In January 2004, two cyclists in the Cofidis team, which is one of the top teams in france, were caught as drug abusers for EPO and amphetamines. 7. Steroids in baseball (5) In 2002, a report was published by the Sports Illustrated and the National League MVP Ken Caminiti stated that â€Å"at least half the guys are using steroids.† In 2003, the Major League Baseball revealed that around 7% of 1438 tests on all players were positive for steroids. 8. Doping in skiing(5) Drug abuse in cross-country skiing has been spread for years especially with EPO. In 2001 world championships in Finland, six finish skiers have failed drug test for HES which is a plasma volume expander. Three skiers at the Salt Lake Games were tested positive for the drug Darbepoetin which is a synthetic compound of the natural hormone EPO. Two of these athletes Olga Danilova and Larissa Lazutina were Russian medalists but later on, they were stripped of their medals and the gold medal was awarded to the Canadian Beckie Scott who ended third. 9. BALCO scandal BALCO is Bay Area Laboratory Cooperative which is a company that provides nutritional supplements. Victor Conte built BALCO in 1984 and he followed a system for analyzing urine and blood in order to prescribe supplements that replace vitamin and mineral deficiencies. Tetrahydrogestrinone is one of banned substances that was used by BALCO and was undetected by drug testing. THG or â€Å"The Clear† is an anabolic steroid that can reduce fatigue during training and can increase the muscle mass. In 2003, the USADA, United States Anti-Doping Agency, developed a test for THG after receiving a syringe from anonymous (US track coach Trever Graham) containing THG and claiming that most athletes are using this drug. Don Catlin, succeeded in developing the test and he tested the urine samples that were taken from athletes at the US championships and numerous tests came back positive for THG(8,9). Athletes that were involved in BALCO scandal were Kelli White, Marion Jones, C.J.Hunter, Tim Montgomery, baseball star Barry bonds, and NFL’s Bill Romanowski, and Dwain Chambers. In 2004, Dwain Chambers who was the European 100m championship at that time was banned from competition for 2 years. 100m and 200m Champion kelli white was banned for 2 years as well. USADA convicted BALCO, for the distribution of THG. In 2005, Victor Conte was jailed for four months. Greg Anderson (Barry Bond’s trainer) was jailed for three months.(9,10,11,12) 10. Ma’s runners Ma Junren was the coach for the world female championships runners(13). In 1993, Ma’s Chinese female runners won three gold medals at the World Track and Field championships in Stuttgart and also in 1997 they set world records. From that time there was suspicion that the runners were using banned substances(13,15). A doping scandal for Ma’s runners arose before the 2000 summer Sydney Olympic(14,15). Top runners like Liquing Song and Lili Yin had failed drug test for testosterone during an out-of competition testing in 2000 and the Ma’s Chinese runners were evicted from the Olympic team(13,15). History of drug testing: Doping was also done for race horses not and only for humans. The first drug test was done for alkaloids on the saliva of horses in 1910 by a Russian Chemist in Vienna.(1,2) Drug testing on human urine started in 1950s after the wide spread abuse of amphetamines. (7) After British Tommy Simpson death from amphetamine abuse at Tour de France in 1967, IOC established the Medical Commission and a list of banned substances was established by the IOC. Professor Beckett was a member in the Medical Commission at that time and he developed methods for detection of stimulants ,i.e. drugs that were used† in competition†. (3,7) Methods of Beckett for drug testing were first used in 1968 at Mexico City Olympic competition and these tests were for non-steroidal drugs (narcotic analgesics and stimulants) and there was no tests for anabolic steroids.(7)(3). The first formal drug testing programmes for narcotics and stimulants was in 1972 at Munich Olympics. These tests were done at the competition periods. The abuse of Anabolic steroids became prevalent in 1970s and its use was banned in 1974 by the IOC and added to the list in 1975(1) p313. The first formal steroid testing program occurred in 1976 at Montreal Olympics using radioimmunoassay screening for detection its presence and GCMS for confirmation. (7,19) In and out of competition testing: At first testing programmes were based on tests during the competition periods. But later on it was recognized that these tests were of limited value to catch up the cheats. Athletes learn how to defeat the testing programmes by calculating the clearance time of the drug in the body so they could avoid its use before the competition periods. Form here came the â€Å"out -of -competition† testing programmes to catch the cheats for drug abuse. â€Å"Out of competition testing† started in late 1970s. The first out of competition testing was conducted in 1977 by Norway and in UK, it started in early 1980s. However, the â€Å"out- of -competition† testing did not expand globally until the establishment of WADA in 2000. WADA established out-of-competition testing programmes and it was followed globally from that time.(1) p314-315 Classification of Abused Drugs Doping classes and methods examples Anabolic steroids Testosterone, nandrolone (discussed later Blood Doping blood transfusion(discussed later) Stimulants Amphetamine, ephedrine, cocaine, caffeine Narcotics Morphine, Methadone, Codeine Peptide and glycoprotein hormones Human growth hormone, corticotrophin, human chorionic gonadotrophin, erythro poietin Diuretics and masking agents Acetazolamide, Furesamide, Probencid Beta- blockers Atenolol, Propanolol, Metoprolol Atenolol, Propanolol, Metoprolol Anabolic steroids (discussed later) Blood Dopping (Blood Transfusions) ( discussed later) Central Nervous System Stimulants Athletes often use stimulants to enhance alertness and reduce fatigue i.e. increase physical and mental performance.1p41. These are more used on the day of competition to reduce the sensitivity to pain of athletes if they got injured; however, nowadays they are used during training to increase training time. Amphetamines Amphetamine is a synthetic compound (1920), it was developed as an appetite suppressant and for treatment of narcolepsy, to fight fatigue and to enhance alertness, but later it was withdrawn from clinical use due to the development of tolerance. P42 Methamphetamine is very addictive stimulant, related to amphetamine with more longer lasting and toxic effects on the CNS. Mechanism of action: These are indirectly acting sympathomimetic amine. They enter neurons and act presynaptically to release stores of noradrenaline, and dopamine from nerve endings; they also block noradrenaline and dopamine transporter reuptake and inhibit MAO. They include Dexamphetamine, Methamphetamine, Phenmetrazine, and methylphenidate. Routes of administration: Amphetamine can be administered orally, nasally, and intravenously. Amphetamine itself is not very effective if smoked. Methamphetamine is smokable form and it is becoming increasingly popular as a drug of abuse. Effects of Amphetamines in Sport: Athletes often use amphetamine to reduce fatigue, increase alertness and concentration, increase euphoria and to tolerate painful injuries.p42. p72 Side Effects: The most important side effect is heart stroke.p72. Amphetamines cause peripheral vasoconstriction and thus increase blood pressure. The body overheats and cannot regain its temperature resulting in dehydration.1.p42 The second side effect is that the euphoric action may affect the awareness of athletes and thus they fall in misjudgements. Cases of amphetamine abuse: Amphetamine use was spread around the time of the Second World War, to decrease fatigue of the troops. Later, its use was spread among athletes in 1940s and 1950s. 1.p30. its use atarted to be controlled under the UK Misuse of Drugs Act 1971. In 1960, the cyclist, Knud Jenson, died due to amphetamine abuse in the intense summer heat of Rome Olympics.1p72-30 In 1967 Tour de France, the British cyclist, Tommy Simpson, died as a result of amphetamine abuse while climbing the infamous Mont Ventoux. His death was due to cardiac arrest.1p72 In 1997,American Footballers, (Clarkson and Thompson), withdrew from play due to amphetamine abuse which was taken to tolerate injuries.1p72 Effect on behaviour Mandell (1979), Golding(1981) In 2002, the British skier Alain Baxter, had lost his Olympic bronze medal and he was banned from skiing from March until June, due to positive test of Methamphetamine( l-form which is found in OTC vicks inhaler. IOC test do not distinguish between l- and d- form. D-form is used as performance –enhancing drug. Later on, Baxter’s name was cleared as being a drug cheater and it was approved that the drug was l- form.(16,17,18) Ecstasy It is a synthetic amphetamine derivative. It was synthesized in 1914 as an appetite suppressant. It has stimulant amphetamine like properties, now commonly used in dance clubs but it may be misused by athletes. In UK, it was classified as an illegal substance since 1977, and in USA its use was under control since 1985. Since 1990, there were no reports for ecstasy misuse by athletes.p73 Ephedrine and related compounds Ephedrine is a natural product occurring in the plant genus Ephedra. Phyenylpropanolamine and pseudoephedrine are synthetics. These are used to treat cold symptoms as bronchodilators.1.p73.p42. Mechanism of action It has sympathomimetic action. These deplete noradrenalin from neuronal storage sites resulting in indirect effect on sympathetic neurons and CNS.1.p73 Routes of administration Ephedrine and phenylpropanolamine are found in cold medications (in UK and USA) which are taken orally. Phenylpropanolamine is now prohibited by US authorities. 1.p74 Effect of Ephedrine in Sport Ephedrine is misused by athletes for its euphoric action.1p42. Athletes try to misuse ephedrine because its use could be negotiated due to its presence in the over-the-counter medication.1p42 Side effects The main side effect is the cardiac arrthythmias. Cases of Ephedrine abuse Pseudoephedrine, phenylpropanolamine, and phenylephrine were removed from WADA list for banned substances in 2004, but they are still controlled by WADA for athlete’s misuse. Ephedrine is still on the banned list.1p76 In 1972 Olympics, the US swimmer, De Mont, was banned due to urinary ephedrine positive test in which he declared that its presence due to a medicine.1p76 In 1988, Linford Christie, at Seoul, was tested positive for cold cure substance, and he was nearly to lose his silver medal. Cocaine Cocaine was a component of Coca-Cola until it was classified as an illegal drug and it was removed in 1903.(1)The main therapeutic effect is its use as a local anaesthetic. Mechanism of action Cocaine exerts its sympathomimetic central effects by inhibiting the reuptake of noradrenaline, dopamine, and 5-HT into presynaptic terminals of the mesolimbic reward/pleasure pathway. Routes of administration â€Å"Snorting† is the most common route of administration of cocaine. The powder is drawn up to the noise, and is absorbed through the nasal epithelium into the blood. It reaches the brain within about three minutes. It can also administered by intravenous injection, reaching the brain in 15 seconds and the effects last for 15 minutes. Crack cocaine is smoked in a pipe, absorbed rapidly in the lungs and reaching the brain in about 5 seconds. Effects of cocaine is sport It was misused in sport due to its euphoric effect and due to reduction of fatigue. Side effects Its side effects are: tachycardia, hypertension and at high dosage, tremors and seizures may occur. Cardiotoxic metabolite may result due to concomitant use of cocaine with alcohol and anabolic steroids. Reported cases of cocaine misuse Len Bias, the US basketball player, and Don Rogers, the American footballer died from cocaine abuse.(1) Caffeine Caffeine is the most popular used drug which is found in many beverages like coffee, tea and soft drinks. Caffeine was banned by IOC but then it was withdrawn from the list by WADA in January 2004. However, its use is still monitored by WADA. Quantitative measurement for caffeine in the urine was established in 1984 at the Olympic Games in Sarajevo and Los Angeles. IOC set the level in the urine at 15 micrograms per millilitre and then in 1988, it was decreased to 12micrograms per millilitre. Studies showed that 1000mg doses of caffeine are required to excrete caffeine in the urine at levels more than 12 micrograms per millilitre. Routes of administration It is taken as tablets or injections(1) Effects of caffeine in sport High doses are required in sport to decrease fatigue and increase concentration.(1) Side effects tremors Narcotic analgesics These are called opiates. Raw opium contains morphine and codeine which have strong analgesic properties. Drugs that are usually misused are: Morphine, heroin, and methadone. All opiates were banned by IOC except dextromethorphan, pholcodeine, and diphenoxylate. Codeine was first banned but because many sports federation had refused that so it was then removed from the list due to its presence in many over-the-counter medications. Mechanism of action: Opiates bind to specific opiate receptors in the brain and spinal cord, and also interact with endogenous opiate peptides, enkephalins and endorphins, in mediating emotional highs and in the process of addiction.p(1)-23 Routes of administration Opiates are taken orally, by injection or by inhalation. Effects of narcotic analgesics in sport These are used for their euphoric and analgesic actions. They are used to mimic the injury during training or competition. Side effects These include vomiting, diarrhea, dry mouth, skin itching, loss of concentration, drowsiness, comas, and addiction. At high doses it may cause respiratory depression.(1) p24,,BBC Diuretics and other masking agents Diuretics are drugs that are used by people to remove fluid in order to decrease blood pressure. Examples are: furesamide, acetazolamide and chlorthalidone. Effects of diuretics in sport Diuretics are misused in sport to overcome the side effect fluid retention that is cause by athletes misusing anabolic steroids. They are also used to lower the athlete’s weight in sports that competition occurs in weight groups. P46red and BBC. Also diuretics are used to increase the flow of urine and hence increase the rate of excretion of abused drug or its metabolite in the urine so the abused drug could not be detected. Side effects These include: muscle cramps, dehydration, headache, nausea and kidney damage. Probenecid is used as making agent to disguise the presence of banned drugs and their metabolites by inhibiting the excretion of these through the kidney.p47 red. Probenecid is no more used because the use of gas chromatography and mass spectrometry can detect its presence and catch up the cheats. Beta blockers These were added to the list of doping classes in 1985. But because of its therapeutic use, the IOC in 1993 added them in the â€Å"classes of drugs subject to certain restrictions â€Å"part . They were used by athletes to increase their performance by increasing the cardiac output increasing blood flow to muscles.p-48-49 red Peptide and glycoprotein hormones These are natural substance that are produced by the body.BBC –doping I sport Effects in sport Corticotrophin: it induces the release of the adrenal corticosteroids thus mimic the pain after injury. (1)p47 Human Growth hormone(HGH) and chorionic gonadotrophin( HCG) : it has anabolic effect, so it increases size and strength of muscles. BBc Erythropoietin: it is a peptide hormonep48(1). It increases red blood cell production thus increasing the oxygen transfer by blood ,ie. Increase in the performance .BBC. Side effects HGH has main side effect that is, it may cause acromegaly.BBC EPO has main side effect that is, it may thicken the blood, resulting in heart attacks.BBC Chemical and physical manipulation It is the changing of urine sample by using substances or procedures in order to conceal the detection of a banned substance. Examples of manipulation are: the use of other’s urine, use of vinegar to affect the urine, epitestosterone to alter the ratio. BBC news,doping Anabolic Steroids What are Anabolic steroids? Testosterone was isolated in 1935.(2)p52. It is an endogenous steroidal hormone male hormone produced by testes in men. steroid 7. It is synthesized from cholesterol like all other steroidal hormones. Steroid 7. Epitestosterone is a testosterone isomer and found in a small ratio with respect to testosterone. Steroid7. Testosterone is responsible for the androgenic and anabolic effects.steroid7. The androgenic functions of testosterone are responsible for the modifications in the primary sexual male features. Steroid7. , while the anabolic effects are responsible for enhancing muscle growth, protein synthesis and erythrocytes. steroid 7. Anabolic steroids are group of synthetic modified derivatives of testosterone. steoid 10. When administered, they bind to the androgen receptors which are found in the prostate, skeletal muscle and central nervous system to give their mechanism of action. Their structure is developed and modified to improve the anabolic effects with decreased androgenic effects. steroid 10 Routes of administration Anabolic steroids are administered orally or intramuscularly. Nowadays, athletes are using transdermal patches, sublingual tablets, nasal sprays, and dermatological gels of testosterone to escape positive tests(2). P 3 Why do athletes misuse anabolic steroids Athletes use anabolic steroids due to their anabolic effects, so they are used due to its positive effect on the skeletal muscle tissues. They are used to increase strength and muscle size. They are also used to increase body weight, protein metabolism and collagen synthesis. Steoird 6 and 35 . Some athletes use anabolic steroids because they â€Å"want to be big†. steroid 7. Side effects Cardiovascular effects: Anabolic steroids ingestion results in severe coronary heart disease. They reduce high density lipoprotein (HDL) and increase low density lipoprotein (LDL). Steroid 25- steroid 7. resulting in atherosclerosis. Increase heart stroke Anabolic steroids increase blood clotting and thus favouring thrombosis resulting in heart attacks. steroid 26 Liver problems Oral anabolic steroids results in cholestatic hepatitis and jaundice. steorid 7,26 Also increase in the liver enzymes( aspartate amino transferase, alanine amino transferase and lactate dehydrogenase) is encountered with the use of steroids. steroid 37 Sexual side effects High doses of anabolics in a study by Holma, shows that the sperm counts decreased by 73% and azoospermia occurred for 3 individuals i.e affecting fertility. Steroid 7 They affect secretion of the reproductive hormones like testosterone and thus reducing libido due to decrease level of luteinizing hormone (LH) and follicle stimulating hormone(FSH).sterodi 37. Anabolic steroids abuse may result in prostate cancer. Steroid 37 Gynaecomastia It is the enlargement of the mammary tissues in men due to transfer of androgens to estradiol and estrone. steroid 7,37 Psychological effects A study in USA showed that anabolic steroids revealed changes in mood such as mania and depression. steorid7 Other side effects include: hyperinsulinemia, hypertension, tendon damage, steroid 26. edema, muscle spasm, acne hirsutism, and deepening of voice. Steroid 35 History of anabolic steroids misuse and drug testing The use of banned substances such as caffeine, cocaine and strychnine started during the 19th century in most of the sport events like cycling, swimming, and distance running. steroid 26. The abuse of steroids in sport started in 1950s by the soviet weightlifting teams.p54 green,steroid26. In 1960 Olympic Games, anabolic steroids use was restricted to Soviet weightlifting, but by 1964, their use is increased in all strength sports. p45 green. 7. Anabolics use became more common in most sports in 1972 Olympic Games. Steroid 26 Anabolic steroids use has been banned by medical commission of IOC in 1974 and has been added to the list of banned substances of IOC in 1975.steroid 10, 7 Although the first formal testing was introduced in 1972 Munich Olympics, there was no testing for anabolic steroids (7). P4. The first formal test for anabolic steroid was in 1976 Montreal Summer Olympics(7). First positive tests for steroids were in 1976 Montreal Olympics, in which 8 athletes, seven weightlifters and one female athlete in a field event were caught for steroid abuse(7).p75., while no positive tests were reported in 1980 Moscow Olympic Games. Anabolic androgenic steroids are one of the most widely used drugs by athletes to enhance their performance and physical appearance. Steroid 6. Their use extends to be not among professional athletes but also among high school male and female students. Steroid 26 WADA accredited laboratories published statistics form 1993 till 2003 and this showed that anabolic steroids are the most widely used banned substances.p32.red. 1993 1994 2001 2002 2003 stimulants 22.8% 24% 15.4% 14.9% 19% Anabolic steroids 59.9% 50.5% 40.1% 36.8% 32.1% Unlike amphetamines and other stimulants which were taken on the day of competition ( which causes sudden death due to cardiac arrest), anabolic steroids are administered during the training exercise and not before the competition periods. P31 red. they are taken in cycles with duration of six- twelve weeks, and usually 2-3 cycles are taken in a year. Steroid7. The introduction of the â€Å"out of competition† testing programmes limited the use of the anabolic steroids. P46 red Systematic doping: biggest scandal One of the biggest scandals for steroid abuse was in the German Democratic Republic, they were used from 1965 to 1989 and this allows the East German to win many medals. Coaches and doctors in East Germany follow a programme for systematic doping with steroids. In 1965, a pharmaceutical company had developed chlor-substituted derivative of methandrostenolone (Oral-Turbinabol R), and from 1968 GRD started to introduce it to female athletes in the Olympic Games. Steroid 40 Detection of anabolic steroids: Detection of urinary anabolic steroid by radioimmunoassay Drug testing was based on radioimmunoassay screening of urine samples from athletes for detection of banned substances and then gas chromatography/mass spectrometry for confirmation the positive tests (7). Testing at that time was insensitive and not selective due to the fact that testing was done during competition periods and anabolic steroids were usually taken for long periods, so athletes used to quit these drugs at competition periods so their level will decrease in the urine and could not be detected and the tests would give false negative (19). Detection of urinary anabolic steroids by GC/MS, measuring testosterone to epitestosterone (T/E ratio) Drug testing at that time could not differentiate between endogenous testosterone and synthetic anabolics.steroid7. Testosterone was introduced in the banned list of IOC in 1983, it was the first endogenous substance to be banned, after the discovery of the detection method in 1982. p35red. In 1984 Olympic Games, all urine samples from athletes were screened by GC/MS for detection and identification. The T/E ra

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I would like to present myself as a prospective candidate for Master’s Program in Mechanical Engineering at Masdar Institute of science and technology. I graduated from NED University of Engineering and Technology as a Mechanical Engineer in December 2011. The reason I opted mechanical engineering was my inclination towards the subjects relating mechanics of solids. My interest in this field grew to such an extent that I became passionate of taking the knowledge gained in the classrooms to the next level and was successful in securing the final year project of â€Å"Designing of Pipeline for Refinery Effluent†, a real time industrial assignment of Pakistan Refinery Limited which is considered as one of the leading oil and gas companies in Pakistan. To secure such an industrial project, which not only needed research potential but also the aspect of understanding the dynamics involved in the industry, I prepared myself during my bachelors by participating in numerous projects and received multiple national awards for my work, as a leader and a member of team for the design and fabrication of unmanned aerial vehicle (UAV) in DBFC (Design Build and Fly) organized by the American Institute of Aeronautics and Astronautics (AIAA). I was also selected for the renowned international competition Shell Eco Marathon Asia, to design an energy efficient car. These projects not only gave me hands-on experience in dealing with composites and testing my knowledge, they also gave me the chance to explore the field of fluid mechanics and aerodynamics. Along with these notable competitions, I regularly took part in local engineering competitions and seminars to actively apply the knowledge I gained during my bachelors. Having done these mechanical ... ...ill help me in understanding the analytical techniques and instruments, while my software skills will assist me in handling the problems related to modeling and simulation. It will also enable me to execute the challenging tasks to the fullest of my abilities. I believe Masdar Institute is the perfect institute which provides the right blend of research and academics needed in the professional world and I am hopeful that this combination would prove to be an asset for me in the future to come. I envision a career in this field as a culmination of my interests and I would appreciate the opportunity to pursue this at Masdar. Admission in the master's program at this esteemed institute would be a milestone in my academic, professional and personal life and ambitions. If accepted, I will be dedicated to perform at a level that will make both the university and I proud.

Telemachus – Good or Bad Brother?

Siblings are the people we practice on, the people who teach us about fairness and cooperation and kindness and caring quite often the hard way. Pamela Dugdale (Blog writer) Would Telemachus be a Good or Bad Brother? Imagine for a moment what would happen if Telemachus, Odysseus’ son, â€Å"The Odyssey† by Homer, had a younger brother or sister. How would his life change if he knew he has somebody to protect? Or if he knew he has somebody to pass the reins of power to? Probably he could be braver by knowing he is a live shield for somebody.On the other hand what would happen with his temperament if he had an older brother or sister? There is a chance he would be mentally weaker. Maybe he would blame his sibling for all of his troubles. In order to find answers to these questions I will be presenting you bare facts from research studies made by different people in different centuries. I am also testing my own experience and ability to understand this precious bond betwee n siblings and family members. I am an older brother to my two younger lovely sisters. While I was growing up I was still the only child, but I was like an older brother to my two dear cousins.Family bond is a special thing. Whenever you speak to your close family member whom you haven’t seen for a while, you are most likely to take his or her words deep into your heart. That’s why silver-eyed Athena uses form of Iphthime, Penelope’s sister, in order to convince Penelope. And I will do my best to describe lonely prince Telemachus’ character and apply it to the whole different environment, which will show the peculiarity of growing up with siblings. Let’s imagine him sharing not only common moment of happiness and joy, but bitter sweet moments of grief and sadness.Depending on what kind of person his sibling would be, Telemachus could possibly show us some of his negative qualities. Because I think Telemachus would be too modest to be in charge of t he family, I feel like his sibling would overpower him. But in some ways better than his father, loving and generous person Telemachus would become a good brother! There is an interesting article I read that I would like to share. It is called â€Å"siblings relationship† and for its most part it is summarizing article that gives a reader a broad view of siblings’ behavior in a family.Here are some interesting moments: â€Å"The earliest research on relationships among siblings developed the common theme that brothers and sisters relate to each other mainly in a rivalrous way, competing for parental attention and status within the family unit. It is true that young siblings frequently fight with each other, putting a strain on the entire family; in fact, family psychologists report that squabbling among siblings is one of the top concerns of their clients†(sibling relationship). It is true that rivalry exist within any family with two and more kids.But scientist s, in their materialistic nature, will always be looking for sources and reasons why it happens. The old opinion is formulated by Alfred Adler in 1959. Adler says, â€Å"that the ‘dethronement’ of the eldest child by the birth of a sibling is a trauma that initiates all sibling rivalry† (sibling relationship). This opinion is pretty narrow. Newer facts that we get fromâ€Å"Some studies show that those siblings who exhibit the most rivalry are also the most likely to cooperate, be affectionate, share, and support each other†(sibling relationship).Meaning it helps kids to develop good qualities such as ability to share, compassion, consideration and patience. My interpretation of it is as follows: if two brothers are fighting over a bicycle and an older brother always gets to ride it and he does it day after day. Until he gets to the point when he starts realizing that he makes his brother sad. This is a moment when older brother’s personality is sta rting to change. Maybe he will not change his behavior right away, because there is usually too much rivalry going on between brothers.So it’s up to older brother to change first, but both of them will carry an understanding of the importance of sharing into adult life. In a similar way siblings learn how to solve relationship problems that may happen in their future. When interviewed one old couple said, â€Å"The Secret of Our 78-Year Marriage? Argue Every Day†(101-Year-Old Married Couple). I would like to come up with an only child in a family study in order to better understand Telemachus.There is a stereotype that children have a better chance to grow into healthy adults if they have siblings. â€Å"The only child is popularly considered to be selfish, lonely, and maladjusted† (Falbo). This opinion was around for more than a hundred of years since the first studies in 1880’s. Nowadays the studies show only child in family usually performs better in s chool and is more likely to achieve expectations of their parents. Don’t get me wrong here; I think siblings gain better qualities in their childhood than only child.When siblings grow up and become adults they tend to be emotionally strong and prepared for relationship issues that are inevitable. On the contrary, the only child is not emotionally prepared and will have expectations of everything and everyone to be near to perfect. The moment something goes wrong it is harder for the only child to accept it and work on that emotional problem. In an article called â€Å"Only child syndrome a myth† the author crashes the myth of the only child not having enough friends.Nonetheless there are some interesting facts in the article. It says, â€Å"A study of kindergarteners, published in 2004 in the Journal of Marriage and Family, found that teachers rated sibling-less children lower on a variety of social skills, including self-control and interpersonal skills† (Sohn ). For a moment imagine this happens in 2004 when there are a lot of pre-school classes for kids and day-care centers, but back on Ithaca years and years ago Telemachus probably had not many kids to play with.Laura Padilla-Walker at Brigham Young University made an interesting research †She recently found that having affectionate siblings helped kids, ages 10 to 14, feel less lonely and depressed and act more generously† (Sohn). It proves the already mentioned statement that siblings are learning how to be generous just by living together. Here is another important statement that she makes,† If parents only have one child, they will just have to work a little harder to give children those opportunities (Laura Padilla-Walker)† (Sohn).I think these words would be true about Penelope working hard to establish good social skills in her son’s mind. I assume that all the credit gets Penelope for growing a fine son like Telemachus, but maybe it happened thank s to Eurycleia’s care and love. Eurycleia is on Odysseus’ nurse. Nonetheless, there is no clear answer in here. Interesting facts were published in North American Journal of Psychology. â€Å"Adult siblings can be essential resource for support, love and friendship (Van Volkom, Machiz and Reich). This many studies supporting my idea that having a sibling is so many ways beneficial. When siblings do not have a good relationship with their parents, they tend to overcompensate by having a supportive relationship with one another. Support and warmth is different between men and women (Van Volkom, Machiz and Reich). This makes me believe that Telemachus would be even closer with his sibling because they both would share the pain of growing up without father. â€Å"Living through traumatic life experiences together makes the sibling bond stronger† (Van Volkom, Machiz and Reich), that would be living in a house that is invaded by suitors in Telemachus' case.The resear chers found out about â€Å"the ‘love and hate' pattern that frequently occurs in the sibling relationship† (Van Volkom, Machiz and Reich). But â€Å"positive outcomes can result from rivalry† such as â€Å"learning how to share and compromise† (Van Volkom, Machiz and Reich). I would like to summarize the whole article. The studies made are showing that â€Å"overall, most participants reported that rivalry peaked in either childhood or adolescense normal), and then declines in adulthood as siblings come back together as friends† (Van Volkom, Machiz and Reich).I think this research is supporting my two previous researches and brings up new facts to think about. There was a moment in The Odyssey that simply shows why it is good to have a sibling in this life. Bright-eyed Athena decided to help Penelope by cheering her up and encouraging her. Athena creates a phantom of Penelope’s sister Iphthime, then phantom enters Penelope’s dream. So Penelope is dreaming, tired of endless crying, and suddenly her beautiful sister, the person she can trust and believe, is in her dream.And so Athena inspires her, â€Å"Your son will still come home – it’s decreet†¦He travels with such an escort, one that other would pray to stand beside them. She has power-Pallas Athena†(4. 907-932). These words spelled from her sister’s lips inspired her like nothing else in the world. Athena reached deep into her heart, bringing love there and flaring a small light of hope into a huge fire of belief. Sometimes it’s good to have somebody to remind you about how beautiful life is and that you are not alone because you have your wonderful brother or sister. Now, imagine Telemachus growing up with his older brother.Finally he has somebody to talk to, but I think Telemachus would be blaming his brother in the same in what he is blaming suitors and gods. Here is what he says to his mother, â€Å"why, mother/wh y deny our devoted bard the chance to entertain us any way the spirit stirs him on? Bards are not to blame – Zeus is to blame. He deals to each to each and every laborer on this earth whatever doom he pleases† (1. 395-403). Maybe he would accuse his older brother of not protecting their mother. It might also happen so he would proceed with Athena’s plan behind his brother’s back.But otherwise, I think Telemachus would die for his brother, here what he says when he is protecting his father,† Ctesippus, you can thank your lucky stars you missed our guest – he ducked your blow, by god! Else I would have planted my sharp spear into your bowels†¦and I’d rather die, yes, better that by far then have to look on at your outrage day by day†(20. 340-354). Telemachus is brave, though he grew up without father or sibling, but I can only imagine how much more courage he would have gained having his older brother by his side. Maybe they wo uld be plotting the same plan on how to get rid of suitors together.Of course, it all depends on what kind of person his brother would be. Just a little different situation would occur if Telemachus suddenly happened to have a younger brother or sister. Definitely, he would not sit around with suitors, as he does day by day. He complains to Athena,†Soon – you wait – they’ll grind me down as well† (1. 293) He would have never said that if he would have clear goal to protect what is precious to him. It’s like a duty of older brother. He would understand he must act in order to save the future of his sibling.I would like to add two more qualities that can be learned being a brother from my own personal experience. I am an older brother to my two sisters five and six years old. Beside that I’m an older cousin to my two other cousins. We were three boys growing up together. Being an older brother is learning how to be patient. I was growing up with only one sister. But even that one was enough. Looking after that small yo-yo takes nerves made of steel. From love the patience is born. And through patience a lot of things can be forgiven. Things like, turning off my computer while I’m playing my favored video game, which my sister enjoyed to do.As for being an older cousin a different lesson is taught. I did hurt my younger cousins and I do pity it a lot by now. I wish I wouldn’t be so harsh older brother as I was. When you have power over others it takes time to understand how to not overuse it. After doing a research and looking into Telemachus’ character I can surely say he would be a great brother. He would team up with his older sibling against suitors. Be it a brother, they would make a plan on how to slaughter suitors. If a sister, they would look for some help outside or maybe in some tricky way would have poisoned them.If a sibling would be a strong person, Telemachus would double his or her qualities making them twice stronger and wiser. If a sibling would be weak person, Telemachus would be ready to take over the responsibilities. In a last situation the sibling having a reckless life would have caused Telemachus into even greater depression. Having a younger sibling would bring great benefits to Telemachus. He would gain qualities like supportiveness, patience and self-confidence. Because he would be in care of somebody he would become more reliable. He would be more responsible for his words and he would support his words with actions.If he had an older sister she would give him a good emotional support. Overall, Telemachus would become a man that is ready to accept and fight off his problems in a manly manner. In general having a sibling is most likely to have a positive effect on one’s personality. This belief is so strong in our society that many couples decide to give birth to a second child. Nowadays studies prove that sibling relationship is not that e asy. Usually there is a lot of rivalry going on between siblings in adolescence, but it mostly results in strengthening the bond between siblings.Other studies are trying to prove that only child is happier and performs better in school, but my opinion is growing up with sibling is a lesson that is priceless in a school called â€Å"life†. I value the sibling’s experience 5 times higher than only child having a happy childhood. So might some of us that grew up as only child have to think to themselves: â€Å"Do I have to catch up with those people who grew up with a sibling†? Works Cited Falbo, Tony â€Å"The One-Child Family in the United States: Research Issues and Results† Studies in Family Planning Vol. 13, No. 6/7 (Jun. – Jul. , 1982), pp. 12-215 Web. 11 of April 2012 Homer. The Odyssey. Trans. Robert Fagles. New York: Penguin Classics, 1996. Print. Senior, Jennifer â€Å"101-Year-Old Married Couple† www. nymag. com (2009): n. page Web. 4 of April 2012 â€Å"Sibling Relationship† , N. A. www. faqs. com (2012): n. page Web. 4 of April 2012 Sohn, Emilie â€Å"Only Child Syndrome a Myth† news. discovery. com (2010): n. page Web. 4 of April 2012 Van Volkom, Michel , Machiz, Carly and Reich, Ashley E. â€Å"Sibling Relationship in College years† North American Journal of Psychology; 2011, Vol. 13 Issue 1, p35-50, 16p, 1 Chart, Web. 11 of April 2012

Days of Terrorism essays

Days of Terrorism essays Violent acts such as bombings, assassinations, and hi-jacking are known to be described as terrorist actions. Terrorism is a growing international problem and governments have had little success to resolve issues in which terrorism is used. September 11, 2001, one of the most important dates I will remember throughout my life. It was morning just as I woke up to get ready for school. I was tired and didnt know what was going on. The television was on and the Chinese news was broadcasting live coverage of what is happening to the World Trade Center. The reporter reported that some terrorists hi-jacked an airplane and crashed into the building. When I first watched the news of this live coverage, I knew something was wrong. The Chinese News does not usually talk about United States news that early in the program. When I arrived at homeroom, a television was on broadcasting the same news. At this point, I got more interested in this topic. Because my first block was social studies and the teacher is my homeroom teacher, she allowed the class to watch the coverage live. Later during the coverage, the program announced that another airplane have crashed into the second tower of the World Trade Center. Shortly a fter the announcement, the bell rang and never thought about it until the very next day when the social studies teacher gave out several newspapers from the Times Colonist. At that time, I knew I should not forget about this incident. A lot of people around the world probably have tuned into a news channel during that day. As war on terrorism continues on, I expect many people will tune in to the news as well. ...

Narcolepsy

Narcolepsy Free Online Research Papers Narcolepsy is a devastating disorder that causes uncontrollable sleepiness and muscle weakness. It is the abnormal, uncontrollable tendency to sleep during the day. Someone with narcolepsy experiences episodes of uncontrollable sleepiness that may occur several times during a day. It usually occurs after eating, but may occur at any time, each sleep episode lasts for about fifteen minutes. The person then awakens refreshed, only to become tired within the next hour or so. I can somewhat relate to how narcoleptics feel because I have a somewhat similar, only not as severe sleeping disorder, sleep paralysis. Narcolepsy represents a neurological problem of sleep wake mechanisms in the brain. Some of it’s symptoms are; excessive daytime sleepiness (EDS), desire to sleep longer than the usual seven to eight hours, attack of Rapid Eye Movement (REM) sleep during the day that may cause attacks of muscle paralysis, memory loss, cataplexy (sudden loss of muscle tone), and dream-like hallucinations. As a result of the muscle paralysis, various muscles in the body are affected. Also, because of the dream-like hallucinations the brain and mental status of the person is also affected. Though the worst symptom of all would have to be cataplexy, for it can cause a person’s muscles to completely give out, putting their life in danger with out warning. Though not all of these symptoms occur in all cases, in fact all of them occur in only ten percent of overall narcolepsy cases. Cataplexy is the most common symptom associated with narcolepsy, afflicting over seventy percent of patients. S leep paralysis comes next, occurring in 30 percent of cases, and hallucination comes last, which is present in only 25 percent of cases. Narcolepsy is usually diagnosed between the ages of fifteen and twenty-five. Unlike most diseases, narcolepsy affects men and women in equal numbers. Although the disease is not terminal it can still affect a person’s life greatly. Narcolepsy causes people to have trouble staying awake while doing simple activities, which affects a person’s daily life greatly. It mostly interferes with a person’s ability to work. For example, if you’re a student with narcolepsy it can cause you to lose focus easily, resulting in bad grades. Not only that, but the dream-like hallucinations that comes along with narcolepsy have caused some people to be driven mad, for they cannot discern what is reality and what is not. There are many ways of treating narcolepsy, both medical and non-medical. Some non-medical ways for narcoleptics to prevent sudden sleep attacks are; planning naps so that their body will feel rested when they need to stay awake. They can also take forced naps when they are drowsy to help them function normally. Consuming caffeine in moderation can also help a narcoleptic stay awake. Some medical treatments used for narcolepsy are stimulant pills such as dextroamphetamine, and methylphenidate. Though if a person has cataplexy, a physician will most likely prescribe and antidepressant to suppress the attacks of REM sleep. Some more complicated methods of treating narcolepsy includes cerebrospinal fluid removal, intrathecal injection of air, and X-ray irradiation. Various other effective treatments have been found and experimented on over time but even today the most common are antidepressants and dual stimulants are mostly used on people with narcolepsy. The most recent experiments o n narcolepsy has led researchers to believe that a lack of the brain chemical Orexin may be the root cause of narcolepsy. Though even today there is no cure for narcolepsy so all you can do is carefully treat it. If it is left untreated however, worse symptoms may be experienced such as microsleep, total paralysis, or a total muscular collapse. The first known cases of narcolepsy were reported in Germany in1877by a man named Westphal, and Fisher in the year 1878. The unusual connection between muscle weakness occurring along with extreme sleepiness were proved in their two reports. The muscle weakness is of course referring to cataplexy but it wasn’t given its name until the 1902 by a man named Loewenfeld. Narcolepsy was given its name by a man named Gelineau in 1880; he coined the term narcolepsy from the Greek words â€Å"narke† meaning â€Å"stupor† or â€Å"numbness,† and â€Å"lepsis,† meaning â€Å"to sleep†. Gelineau is also famous for recognizing the disorder as a specific clinical entity. In conclusion, even though narcolepsy is not a fatal neurological disease it still has serious repercussions if allowed to progress to a more advanced stage. It is also probably one of the most dangerous disorders with out a cure, for it entirely affects the brain and a wide range of muscles. In my opinion narcolepsy is one of the most horrible neurological diseases out there, for it completely takes away a person’s ability to function properly and can result in total paralysis, leaving the person to live out their life as a vegetable. Research Papers on NarcolepsyArguments for Physician-Assisted Suicide (PAS)Lifes What IfsThe Masque of the Red Death Room meaningsPersonal Experience with Teen PregnancyThe Effects of Illegal ImmigrationCapital PunishmentThe Fifth HorsemanThe Spring and AutumnGenetic EngineeringMoral and Ethical Issues in Hiring New Employees

Should Gov essays

Should Gov essays Should the Gov't Enforce Their Laws Upon its People. To enforce laws upon a society that does not agree with the laws in the first place is not right. A government is there to represent its people not to contradict them. In order to get people to live in a reasonable society, the government has to be open to the peoples' opinions and thoughts on laws that aren't agreed upon. I agree that some laws prevent life from turning into uttermost chaos, however if a large percentage of people do not agree with a certain law that is clearly unreasonable, life will turn into chaos. Its like fighting fire with water. The government being the fire and the the citizens being the water. The government is strong and has a large amount of authority but if they get out of hand the citizens will wash them out. It seems as if the government manipulates peoples' minds. The government forces the "fact" that if there were not certain laws, people would be out of control, which is not necessarily true. An assumption is that people will go out and irresponsibily do things just because there isn't a law on it. So, if the government abolished the law on gun control, everyone would go out and buy guns and kill each other. Or if there were no laws on drugs and dealing drugs, everyone would be addicts. Obviously there is the percentage of people who do go out and do things that are illegal and if the laws were made legal that does not mean that everyone else would go out and do it too. Laws are supposed to keep life and people in order but what about when people break laws. There is the group of people who do go around breaking laws and there are the people who do not. The people who do not break laws live their life according to the limits and borders the government sets for them. The ones who do break laws go beyond the borders and take the risk of getting caught. The thing is when certain people do go out and break laws, and let's ...

Business Contract (Summarised) Essay Example | Topics and Well Written Essays - 1000 words

Business Contract (Summarised) - Essay Example The client will perform the duties hereby after the commencement of the said contract and these duties will be known as work whereas the usage of these services will be deployed by the aforementioned consultant. The contract is agreed on the following terms and these terms are entitled and subject to complete compliance in all the business scenarios with all the exceptions described in the contract thus hereby a necessity in the business oriented terms. The first and foremost terms of agreement in confidentiality which means the said client and consultant will not breach and exploit any business secrets thus complying full with the legal and ethical standards until and unless the following conditions are being fulfilled up to any extent 2) The exposed content has already been established in the public domain and with the consent of the both the legal business parties thus ensuring no imagery and monetary detrimental consequences to the client and consultant in any possibility 3). The content is exception to the domain which is contained from the third parties and entities which have no legal or authoritative party role to play in the legal terms of agreement. The Approved Salon agree must refrain from any advertising which may damage Shu Uemura’s image by the use of an ostentatious or demeaning presentation that is incompatible with the exclusive and luxury nature of the Products, the prestige of the Brands and the qualitative appearance of the Retail Outlet The Products of the company will be distributed and sold exclusively to Approved Salons of the company which agree to meet the applicable Approved Salon Criteria that will be defined separately and which have been approved by Shu Uemura as fulfilling these Criteria, this being without prejudice to Shu Uemura’s right to engage in direct sales via its own outlets, or through resale to an Approved Salon via exclusive distributors, or via the Internet. Sale of the products and supplies will

The Responsibility Project Essay Example | Topics and Well Written Essays - 750 words

The Responsibility Project - Essay Example He just put a block of carrot in place of the missing wheel to balance the chair. The film ends with the concern being settled because someone was selfless and became willing to sacrifice in addressing the needs of others before his own. The film illustrates negative behaviours within an organization – avoiding responsibility and passing problems to someone else. It shows how the worker who first had the chair problem refused to resolve it and just tried to get away with it. It was not only him but also his coworkers did the same thing. In an organization, workers have the tendency to deny their mistakes and hide them as much as possible. This negative practice would most likely result to unresolved problems and conflicts. It also defies the importance of teamwork and respect for others. Nevertheless, the value of sacrifice and selflessness was also demonstrated in the film, which was another example of lack of cooperation. The film shows how an office can be a better place if only each individual would show initiative, problem-solving skills, respect and concern for others, and equality. It also shows that a particular burden of an organization should not be the burden of only one person, even though he is w illing to take charge of the problem. The film also targets the negative implications of having unresolved problems or unaddressed issues in an organization. The bad habits illustrated in the film, when tolerated, could put the survival of an organization at risk. It shows that the workers could not really be trusted even with a minor setback such as a dilapidated chair. If these practices strongly exist in an organization, they would create an unhealthy and discouraging work environment. The issues illustrated in the film create awareness among viewers that unhealthy behaviour really exists in organizations, thus, encourages us to make ways to

Create your own christian demonology Essay Example | Topics and Well Written Essays - 1250 words

Create your own christian demonology - Essay Example The purpose of this paper is to create a new Christian demonology within a particular period and context. The Christian demonology discussed in this paper belongs to the Medieval Period between the 5th to 15th century around the European region, where the belief in the power of demons and grimoires were widely existent during that era. This demonology evolved from the old Christian tradition, on basis of the scriptures, mentioning that the demons were the rebel angels that were cast down from the heaven by God. Though they are spiritual, immortal and immutable, like the good angels, these demons are not omniscient or omnipotent. As per the Christian demonology, the demons were intended to induce sin into the world by possessing and tormenting people in the world. The ultimate mission of the demons was to abandon the faith of God from the people and turn them into adversaries of God. The demonology of the Medieval Period identified demons as evil supernatural beings, who take control over the departed souls of men or their bodies for executing their evil schemes on earth. According to the biblical notion, they are the inhabitants of the Hell and whoever is possessed by these evil spirits are destined to do whatsoever the demons wish to. The demons were considered as the ‘elements of the world’ as supernatural being living in the air and ruling the entire universe. Paul writes in Galatians 4:3, we were in bondage under the elements of the world, which means that both the physical and spiritual cosmos comes under the power of these demons. What distinguishes this demonology is that the medieval demonology held a demonic plurality comprising not only the fallen angels as demons but also the evil spirits and souls of dead humans, in general. This is far from this demonology, as it takes the stand that the entire demonic world comprises of the fallen rebel angels, taking control over the whole world and the universe, for their evil possessions, after bei ng cast away from the Heaven to Hell. The demons exercised power over the world including the wind, water, air, sand as well as the stars and the entire universe. The peasant communities in this medieval period were particularly concerned of these demons as they hindered the nature. They comprised of various occults, witchcrafts, ritual magic and more for either abolishing or inducing the evil acts of the demons for various purposes. These demons also hold influences over the passions of mind, sexual, mania and melancholy by inflicting pain and pleasure. The witches and occultists make use of these demonic powers to perform their actions, choosing the demon with power of Hell that well suits their operations like seeing the future, seducing the object of lust, finding hidden treasure, etc. As the demons have control over the world, it possesses the humans and takes various physical forms for deceiving the world. In this Medieval Period the demons were believed to be the reason for t he pagan cults and other religious practices. It was thought that these rituals would help to expel the demons, by diminishing their evil acts and possession in the lives of humans. According to them, these cultic practices and rituals were the cause for their worshiping of demons which was indeed viewed as rebellious among the Church and Christian beliefs. Â  However, demonic administration used for handling magic, astrology, and mantic arts

Personal Statement Essay Example | Topics and Well Written Essays - 500 words - 39

Personal Statement - Essay Example More recently, I have begun to excel more in Biology than in Chemistry or Physics and this is where I wish to continue my studies. Biological Technologies is an important field and is fast becoming an important aspect in the industry and to medicine. Specializations such as Bio-Materials and Genetics are seeing significant developments. I believe that there are still many new and exciting discoveries waiting to be found, hidden within nature, and of beneficial use to humans and the environment. It would be beyond my wildest dreams to become a part of the next discovery. A Masters in Biotechnology will enable me to gain the knowledge and skills that I will need in this pursuit. I see my future to be devoted to research. I want the continuous search for new things to be my career. My dream, as many scientists share, would be to discover something that will be ground-breaking and help many people. I aspire to one day go down in history through this, and though no plan is set in stone, I wish to gather as many experiences as I possibly could. For the mean time, I would rather consider all of my options first, as glory will not put food on the table. But I hope in the future to be able to pursue more of the things I am passionate about. I am creative and I have substantial significant technical knowledge of the biomedical science sector. I possess a specialist’s expertise and understanding alongside the skills required to fully grasp it. As an individual, I am not easily put off by challenges. I believe that once you set your heart on something you will be surprised how many problems and seemingly insurmountable obstacles can be overcome. I am reliable, self-motivated and trustworthy. I always aim to work as methodically, efficiently and accurately as I could. I am quick to learn and I am able to comprehend things swiftly. When there is something I am not quite certain of I am willing to ask for help, recognizing other people’s wisdom. I

Real estate national overview Essay Example | Topics and Well Written Essays - 750 words

Real estate national overview - Essay Example In addition to, France hosts a number of NATO agencies, which play a significant role in the development of the group. France is an active part of the modernization process of NATO military (Milligan, 14). The state of the national economy of France is that it is stagnating. It is evident through growth, unemployment, and national debt. According to statistics, the economy of France will hit the European Union budget shortage of 2007 (Murphy, 8). The French believes that an intervention can bring the situation under control. The French president believes that an expansive fiscal policy is essential in dealing with the French economy. France has a GDP of $35700 in comparison to other nations in the region (Boyer, Berend & Haba, 19). The economy of France has expanded its horizons when relating various sectors of the economy. The central government has privatized most large companies in France to allow other stakeholders help the nation to develop. On the contrary, the government maintains to play a significant role in some sectors of the economy. The government manages to hold a majority of the shares in industries such power, transport and defense system. France has at least 82 million foreign tourists annually, and it is the most visited country in the world. France leaders are capitalists, and they have maintained a social equity through laws and policies. The unemployment rate in 2008 rose from 7.8% to 10.8% in 2013(Boyer, Berend & Haba, 19). Despite the slow rate of growth in France, the borrowing rate reduced significantly and attracted investors to the country. The demand for housing in France rose due to the massive demand for houses. The increase in interest rates increased the demand for houses in the nation. The availability of long mortgages has encouraged the demand for houses in France. The financial crisis caused a drop in housing projects in France. In comparisons with other countries, there are many similarities when it

How women are seendepicted in the book the things they carried by the Essay

How women are seendepicted in the book the things they carried by the author Tim O'Brien - Essay Example Only on a few time did you find a woman who in fact fought in the war. Two women from a different source affirmed that "women served alongside men in that sink-pit of War." Some positions women had were non-traditional.The women are a load and a difficulty as much as they are a prompt of what the soldiers required. "All that crap about how if we had a pussy for president there wouldn't be no more wars'' 'You got to get rid of that sexist attitude." These men had a variety of vision and emotion about the women they love, the women they disgust, and the women that they may not be acquainted with and can only vision of. While the text given to the thoughts of women is small is physique, it is fairly important in sense. (O'Brien 1990) Mary-Ann, a seventeen year-old girl from Middle America, rapidly becomes fraction of Vietnam. She studies how to chase from the Green Berets, but almost immediately she shifts further than even them, and disappears into the tropical forest. She loves the way Vietnam makes her experience: this portrays the theme of adultery between her and the soldiers as if she is all there, and can not at all lose herself. 'When her boyfriend last sees her, she is wearing a necklace of human tongues'. Mary Anne Bellgirlfriendto soldier Mark Fossie symbolizes the dishonesty of blamelessness that takes place in war. She appears wearing "white culottes and this sexy pink sweater," fresh from suburban U.S., and becomes a foul tool of bereavement, scarier than even the Green Berets. (Herzog 1992) Yet extra than the American soldiers in Vietnam, Mary Anne Bell symbolizes the unknown, somebody who does not fit in where she is. Like Rat Kiley's troubled reply to behavior process only during the night in "Night Life," the story of Mary Anne highlights what happens when someone's environs have an effect on her. Mary Anne is also symbolic of alteration, specially, the loss of blamelessness to experience. Comparable to how the "green" medic Jorgenson is appropriate to make errors, Mary Anne is greener than any man in the work of fiction. She arrives in Vietnam not only not ready for war but also not aiming to take part in it. Her alteration from an attractive girl wearing culottes to an animal-like huntsman who wears a 'necklace of tongues' equivalents and overstates the revolutionize all young men went through in Vietnam, such as "O'Brien" who went from a boy who was fond of school to the man who planned a aggressive vengeance against Jorgenson. (T O'Brien1991) O'Brien leaves out the ending to the story about Mary Anne, as a replacement for letting her quality pass into the dominion of myths. quite than letting us to know what becomes of somebody (like himself) who experiences an aggressive loss of blamelessness, we are left speculating how war influences a person, and to what ends of time that person will carry on to feel its consequence. The one part of "knowledge" that Mary Anne's story educates us is that once blamelessness is lost, it can never be regained. Different from O'Brien or Bowker, on the other hand, when Mary Anne misplaces her virtue, she becomes a mediator of primitive nature. (Heberle2002) As a final point, Mary Anne is the most genuine instance of love in the novel. Even if Lt. Cross and Henry Dobbins carry memento that remind them of feel affection for, Mark Fossie is the

Personal Statement Essay Example | Topics and Well Written Essays - 500 words - 39

Personal Statement - Essay Example More recently, I have begun to excel more in Biology than in Chemistry or Physics and this is where I wish to continue my studies. Biological Technologies is an important field and is fast becoming an important aspect in the industry and to medicine. Specializations such as Bio-Materials and Genetics are seeing significant developments. I believe that there are still many new and exciting discoveries waiting to be found, hidden within nature, and of beneficial use to humans and the environment. It would be beyond my wildest dreams to become a part of the next discovery. A Masters in Biotechnology will enable me to gain the knowledge and skills that I will need in this pursuit. I see my future to be devoted to research. I want the continuous search for new things to be my career. My dream, as many scientists share, would be to discover something that will be ground-breaking and help many people. I aspire to one day go down in history through this, and though no plan is set in stone, I wish to gather as many experiences as I possibly could. For the mean time, I would rather consider all of my options first, as glory will not put food on the table. But I hope in the future to be able to pursue more of the things I am passionate about. I am creative and I have substantial significant technical knowledge of the biomedical science sector. I possess a specialist’s expertise and understanding alongside the skills required to fully grasp it. As an individual, I am not easily put off by challenges. I believe that once you set your heart on something you will be surprised how many problems and seemingly insurmountable obstacles can be overcome. I am reliable, self-motivated and trustworthy. I always aim to work as methodically, efficiently and accurately as I could. I am quick to learn and I am able to comprehend things swiftly. When there is something I am not quite certain of I am willing to ask for help, recognizing other people’s wisdom. I

How women are seendepicted in the book the things they carried by the Essay

How women are seendepicted in the book the things they carried by the author Tim O'Brien - Essay Example Only on a few time did you find a woman who in fact fought in the war. Two women from a different source affirmed that "women served alongside men in that sink-pit of War." Some positions women had were non-traditional.The women are a load and a difficulty as much as they are a prompt of what the soldiers required. "All that crap about how if we had a pussy for president there wouldn't be no more wars'' 'You got to get rid of that sexist attitude." These men had a variety of vision and emotion about the women they love, the women they disgust, and the women that they may not be acquainted with and can only vision of. While the text given to the thoughts of women is small is physique, it is fairly important in sense. (O'Brien 1990) Mary-Ann, a seventeen year-old girl from Middle America, rapidly becomes fraction of Vietnam. She studies how to chase from the Green Berets, but almost immediately she shifts further than even them, and disappears into the tropical forest. She loves the way Vietnam makes her experience: this portrays the theme of adultery between her and the soldiers as if she is all there, and can not at all lose herself. 'When her boyfriend last sees her, she is wearing a necklace of human tongues'. Mary Anne Bellgirlfriendto soldier Mark Fossie symbolizes the dishonesty of blamelessness that takes place in war. She appears wearing "white culottes and this sexy pink sweater," fresh from suburban U.S., and becomes a foul tool of bereavement, scarier than even the Green Berets. (Herzog 1992) Yet extra than the American soldiers in Vietnam, Mary Anne Bell symbolizes the unknown, somebody who does not fit in where she is. Like Rat Kiley's troubled reply to behavior process only during the night in "Night Life," the story of Mary Anne highlights what happens when someone's environs have an effect on her. Mary Anne is also symbolic of alteration, specially, the loss of blamelessness to experience. Comparable to how the "green" medic Jorgenson is appropriate to make errors, Mary Anne is greener than any man in the work of fiction. She arrives in Vietnam not only not ready for war but also not aiming to take part in it. Her alteration from an attractive girl wearing culottes to an animal-like huntsman who wears a 'necklace of tongues' equivalents and overstates the revolutionize all young men went through in Vietnam, such as "O'Brien" who went from a boy who was fond of school to the man who planned a aggressive vengeance against Jorgenson. (T O'Brien1991) O'Brien leaves out the ending to the story about Mary Anne, as a replacement for letting her quality pass into the dominion of myths. quite than letting us to know what becomes of somebody (like himself) who experiences an aggressive loss of blamelessness, we are left speculating how war influences a person, and to what ends of time that person will carry on to feel its consequence. The one part of "knowledge" that Mary Anne's story educates us is that once blamelessness is lost, it can never be regained. Different from O'Brien or Bowker, on the other hand, when Mary Anne misplaces her virtue, she becomes a mediator of primitive nature. (Heberle2002) As a final point, Mary Anne is the most genuine instance of love in the novel. Even if Lt. Cross and Henry Dobbins carry memento that remind them of feel affection for, Mark Fossie is the

The human nature Essay Example for Free

The human nature Essay How much is human frustration worth? Is it worth losing a chance to buy a present for the girl you like? Or is it worth participating in a lottery which is nothing more but a silly tragic fatal ritual? I was asking these questions while reading James Joyces Araby and Shirley Jacksons The Lottery. For me, both stories represent the ultimate point of human despair: at this point, the person is no longer able to control his (her) life and surrenders under the pressure of overwhelming circumstances. I think that frustration is the central element of both stories; it touches the depth of the readers soul and turns into disruptive revelation about the perversity and hideousness of the human nature. Human strength and endurance has no limits; human evil and self-interest are unlimited, too. James Joyces Araby shows human frustration in its powerlessness in the face of insuperable circumstances. Every morning I lay on the floor in the front parlour watching her door. [†¦] When she came out on the doorstep my heart leaped (Joyce 62). The whole life of the anonymous narrator is filled with joy of seeing the young lady walking in front of him, and passing her before their ways diverge. He lives his life from morning to morning, when he will see Magans sister again. This is the life full of waiting; this is the life full of expectation, anxiety, dreaming and almost physical attraction. The same is the life of villagers whom Jackson describes in her The Lottery. It is the life full of expectation mixed with the feeling of threat, fear, and imminence of the coming end: Bobby Martin already stuffed his pockets full of stones, and the other boys soon followed his example, selecting the smoothest and roundest stones (Jackson 10). As the young boy cannot wait to visit the bazaar I could not call my wandering thoughts together. I had hardly any patience with the serious work of life which, now that it stood between me and my desire, seemed to me childs play (Joyce 63), the villagers cannot wait to hear when the new victim of the annual ritual will be declared: guess we better get started, get this over with, sos we can go back to work (Jackson 13). The deeper Joyce goes into the young boys soul, the larger is the prairie between his promise to visit the Araby bazaar and the realization of his inability to fulfill the promise: Nearly all stalls were closed and the greater part of the hall was in darkness (Joyce 65). How bright and shockingly sincere Joyces revelation could be, Jacksons story has gone far beyond Joyces reasonable limits. Jackson has gone even deeper to the moment of unexpectedness which emphasized the unlimited nature of human mercenary character. In the light of Jacksons The Lottery, Araby produces an impression of the boy’s relatively mild reconciliation with the surrounding opportunities and circumstances. Moreover, I feel that Joyce still leaves some hope that everything will change: ultimately, there will be another bazaar and another girl, although the young boy does not yet understand it. On the contrary, Jackson uses unexpectedness to emphasize how far human coldness, rationality, and perversity can go; the author shows, how easily humans turn into beasts when they pursue material interests, leaving no hope to escape the lottery’s trap. Jackson shows how human desire to kill turns into a usual feeling, when it becomes regular for and acceptable by other community members: the whole lottery took less than two hours, so it could begin at ten oclock in the morning and still be through in time to allow the villagers to get home for noon dinner (Jackson 10). Conclusion Both stories end up in frustration; for Joyces character, frustration is reflected in the hollow sound of two pennies that fall against the sixpence in my pocket (Joyce 66). A creature driven and derided by vanity (Joyce 66) is the end result of Joyces striving towards recognition and love. For Tessie Hutchinson, frustration becomes real as she holds the slip of paper that has a black spot on it, the black spot Mr. Summers had made the night before with the heavy pencil in the coal company office (Jackson 17). Later, this frustration turns into the feeling of inevitability of tragedy, when a stone hit her on the side of the head (Jackson 17). In both stories, frustration is the shocking reflection of the human hideousness, cruelty, and indifference which leave no chance for spiritual and physical resurrection. Works Cited Jackson, S. â€Å"The Lottery†. 10-17. Joyce, J. â€Å"Araby.† 61-6.

Outsourcing: Advantages and disadvantages

Outsourcing: Advantages and disadvantages Outsourcing, advantages and disadvantages Write a 2-3 page paper about outsourcing from the perspective of a multinational firm (Yes, this may be a hypothetical firm), be sure to answer the following questions: 1. What are the advantages of outsourcing? 2. What are the disadvantages of outsourcing? As defined by Chase et al. (2004, 372), outsourcing is an act of moving some of a firms internal activities and decision responsibilities to outside providers. Others define outsourcing as the procurement of the organizations products or services from external sources. Most definitions of outsourcing describe it as referring to allocating or reallocating business activities from an internal source to an external source. The two basic organizations that are involved in the outsourcing agreement are the client firm (the firm that outsources their internal business activities) and the outsource provider (the firm which provides outsourcing services to the client firm). The client firm outsources business activities such as services, manufacturing activities, tasks and jobs. Outsourcing in an international context refers to the outsourcing activity between nations or between boundaries of two or more countries. It includes global outsourcing which involves many international, external firms. Although outsourcing is a new concept, it has been practiced before and was referred to as subcontracting production activities. Outsourcing in an international context has been known as a major driving force in the business world. The Internet has allowed firms all over the world to provide services which were not possible before due to geographical limits. The Internet, together with the WorldWideWeb (WWW) has provided the connectivity that is necessary for the rapid growth of the outsourcing in an international context. Together with the growth of the Internet and WWW is the growth of international business. The passage of international trade agreements such as the 1993 North American Free Trade Agreement (NAFTA) and the World Trade Organization (WTO) and other international trade zones that have been established throughout the globe, governments preparing and allowing the greatest expansion of international business, inexpensive computer and communication technology, have been major contributing factors in the enormous growth of international business. Is international outsourcing desirable or undesirable? There have been many views about outsourcing by multinational firms and a big debate is ongoing across the globe and people are affected by it. Business enterprises greatly support outsourcing but employee unions and politicians oppose it. There are many advantages and benefits that outsourcing can give to the home countrys business undertakings as well as to the country wherefrom the services are being provided. Enjoying cost leadership is one of the ways to enjoy sustainable advantage in this very competitive business world. The best way to achieve this is to outsource jobs. Another advantage of outsourcing is to have greater control over the quality of the goods because they can demand from the many suppliers the excellent products/services at lower cost. The client firm has the advantage of deferred payment thereby creating more opportunities to spend their funds wisely and make it more profitable. Outsourcing can also drive down wage and production costs. Another advantage of outsourcing to the client firm is that they dont need to buy raw materials, and stock them and other semi-finished products in the warehouse thereby saving on space, interest payments, godown charges, pilferage, and wastage. There is also a reduction of the number of people that are employed since the production is done in another place outside of the company. This situation also lowers the headache of union problems. The end result is that the client firm can focus on their core business matters and customer relationship management. Aside from bringing cost savings and an increase in profits to the client firm, outsourcing also brings benefits to the host country in terms of macro-economics. In Information Technology and other accounting tasks that are being outsourced, management of client firm will experience less capital expenses since they dont have to buy hardware and software, less management problems due to having the outsourcing company handle the staff providing the services. In terms of disadvantages of outsourcing, the main argument is the loss of jobs in the country of the client firm as the activities performed in the home country or organizations have been transferred to another location/s. Also, the culture clash that happens between the manufacturing client firm with those doing the outsourcing jobs results in each ones rejection of each ones culture. Another disadvantage is the decline in the labor rate and also, trade unionism gets a jolt due to outsourcing. The state has to pay allowances to the unemployed and all of these disadvantages create problems in society and to the industry side, quality may suffer in pursuit of cost reduction. Another disadvantage is that the client firm will have less managerial control so it will be harder to manage the outsourcing service provider than own employees. The client firm will also tend to depend on the outsourcing provider and if the provider goes out of business for whatever reason, then there is a need to go through a quick transition for another service provider, or find other means so that the business activities will not be disrupted and will go on as effective as it should be. Not all outsourcing can give benefits of cost reduction. Sometimes it can be costly too on the part of the client firm. Other matters related to confidentiality and security issues such as outsourcing processes related to payroll and other confidential information will be known by the outsourcing provider. It might be noteworthy to consider one comment of a business leader that in order to be successful in business, it is better to cut the wastage than to cut costs. Westerners have also expressed their dissatisfaction and unhappiness of the pronunciation and diction of the call centre agents in India and to add to this, there have been instances of leakage and improper use of customers data. Whether the multinational firm will outsource or not, there is nothing conclusive. The firm must perform a comprehensive cost-benefit analysis before deciding on outsourcing. Also, with outsourcing, the days of patriotism and cultural nationalism are gone but what replaces is the satisfaction of the firms own benefit of maximum profitability. References: http://books.google.com.ph/books?id=OYZ_-EiBCJkCpg=PA5lpg=PA5dq=outsourcing+of+an+international+firmsource=blots=HoR0S6CD22sig=cgd7SEV0V3Biegi0RiNSyXnsHnQhl=enei=RvGRSoKzFdOIkQXx_ti7Cgsa=Xoi=book_resultct=resultresnum=3#v=onepageq=f=false http://www.ls-marketing.com/business/tips/advantages_and_disadvantages_of_outsourcing/ http://www.ictstandards.com/Advantages_And_Disadvantages_Of_Outsourcing.htm

Complementary: The Sacred and the Secular Essay -- Religion, Chinese I

Contrary to common belief, religion is composed of both religious—divine reverence, and irreligious elements—politics and philosophy. Reciprocally outlining Chinese ideals, this complementary blend of religious and irreligious elements allude to harmony of opposites without conflict. However, widely interpretative, the Western term â€Å"religion† prevents clear distinction between religion and philosophy when applied to Ancient Chinese religion, Confucianism, and Daoism. Though each equitably dissimilar, each sector influenced the upbringing of the other politically, while continuing to uphold similar purposes of perceived harmony. Therefore, this paper’s analysis of Ancient China’s concept of Ganying, Confucius’ concept of Social Hierarchy, and Daoist practice of internal and external alchemy reveals a progressive religious influence on State, and simultaneously deems philosophy as only an appurtenant to religion. During the Shang Dynasty, Ancient Chinese religion served as the premise to political structure and reign. The first divination process involving oracle bones, or tortoise shells and ox shoulder bones, introduced the idea of Shang diviners. This recognition of power paved way for the separation of social classes, resulting in the elite and popular class. The elite were considered literate and cultivated, comprising the upper class. In opposition, the popular class was that of the lower class, illuminating indigenous values. Exemplifying a religious connotation, prescriptively, the diviners’ chief role during the divination process prompted importance of ancestral worship and sacrifice. Illustrating the concept of ganying, diviners would attempt to provide ancestors with proper sacrifices to induce spiritual fulfillment—s... ...d with qi, jing, and shen, this alludes to the Daoist conservation of blood, semen, and breath. The practitioners preserve these humanly essences through meditation implemented with fasting and breathing techniques (305). These Daoist exercises later influenced and embellished the practice of taji, boxing, yoga, and sexual practices. From China’s most primitive state to its most culturally flourished, when describing Ancient Chinese religion, Confuscianism, and Daosim, individuals regard these practices as a â€Å"philosophy†, or â€Å"way of life†, instead of a religion (105). However, each equally embodies a perennial philosophy—different elucidations symbolize a single, universal truth. Therefore, if religion outlines both religious and irreligious aspects, and concurrently depicts a way of life, one can assert philosophy as an additional â€Å"interpretation† of religion.

Taxes on Cigarettes :: Essays Papers

Taxes on Cigarettes The article â€Å"Smoke Signals†, by the New York Times and the New Jersey Sunday edition, presented an overview of for the state of New Jersey’s recent decline in cigarettes bought in the last year. The article starts off by explaining to the reader how smokers took a financial beating at the cash register every time they went to a convenience store to buy cigarettes. In a smokers reduction movement the state of New Jersey doubled the sales tax on cigarettes forcing smokers to spend an extra forty cents on every pack they bought. Len Fishman, the state commissioner of Health and Senior services, stated that the tax increase was meant to drive down the consumption entirely. As Mr. Fishman traveled around the state he discovered that many people were already trying to quite smoking, they just never had the right physical motivation to pursue their goal. These people explained that the dramatic increase on tax was the finale straw that broke the camels back, and provided the right motivation for them to quite smoking. The tax increase put New Jersey behind only Hawaii and Alaska at $1 a pack, and Washington state at 82.5 cents a pack. Over a six month period the revenue collected from cigarette sales had dropped by 12 percent. For 1998 the revenue earned by cigarette sales should have been roughly 54.2 million cartons, but with the tax increase that number had been dropped to 47.4 million cartons. This gap represents a 6.8 million carton difference, an outstanding decrease in cigarette sales. To all smokers the tax increase means a substantial amount of money will be necessary to maintain their habits. Some smokers will go through great lengths to save as much money as possible, even if it means traveling to other states to buy their smokes. Both Pennsylvania and Delaware reported a significant increase in cigarette sales over the next six months after the tax took affect. Over a one year period Delaware even had a ten percent increase, manly due to the tax increase in New Jersey. The state of Massachusetts raised their tax 25 cents a pack in 1992 and reported a 12.5 percent decrease in sales the following year. Certainly a more alarming statistic is not necessarily how much the tax has decreased the sales of cigarettes, although very impressive and healthy, but rather the percent of under aged children and high school students who already smoke and who are beginning to smoke.